Chemical Characterization and Cytotoxic Potential of a Chloroform Fraction Obtained from Marine Plant Thalassia testudinum | Semantic Scholar (2024)

The cytotoxic activity of T. testudinum marine plant metabolites associated, at least, with ROS overproduction and pro-apoptotic effects is demonstrated and the potential use of these natural products as adjuvant treatment in cancer therapy is suggested.

This review aims to compile the pharmacological activities of numerous seagrass species, their secondary metabolites, pharmacological properties, and mechanism of action and highlights the potency of seagRasses as a promising source of natural therapeutical products for preventing or inhibiting human diseases.

This is the first study which highlights the phytochemical composition of BM-21 and demonstrates that this product is a rich source of natural antioxidants with potential applications in pharmaceutical, cosmetic and food industries.

The results suggest that Ulva fasciata aqueous-ethanolic extract inhibits BP bioactivation and it may be a potential chemopreventive agent.

The results showed that PTE may function as a chemopreventive and/or chemotherapeutic agent in colon carcinoma cells via the reduction of cell viability and the induction of apoptosis via the caspase pathway.

Ulva lactuca the green alga available in Tuticorin coast was found to show anti-inflammatory effect as evidenced by the reduction in the inhibition of oedema at the 4th day of the experiment compared with the positive control drug and control.

This review is presented as a brief survey of recent investigations in the marine pharmacology and discovery of new anticancer drugs to provide baseline information for promoting the marine flora-based anticancer research.

The results suggest that F1 may contribute to skin repair by attenuating oxidative stress due to its antioxidant activity and significantly attenuated the LPO developed following the first 48’h after acute exposure to UVB irradiation.

Wogonin is an active principle compound of the chloroform extract of S. havanensis against P. berghei and T. vagin*lis trophozoites, and the findings suggest that wog onin is potentially useful for the development of antimalarial alternative treatments.

Dichloromethane/Methanol extracts of sixteen species seaweeds collected from the Atlantic coast of Sidi Bouzid El Jadida-Morocco were evaluated for their cytotoxic activity using the test of brine shrimp lethality for larvae and then the most cytotoxicity active species were tested on KB cells line.

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